Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.52 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16185336 | 0.90 | MCL1 (0.46) | GABRA1GABRB2SLC11A2GLASTING1 | |
| SCHEMBL26423718 | 0.88 | GABRA1 (0.52) | GABRA1GABRB2SLC11A2GLASTING1 | |
| SCHEMBL23967898 | 0.88 | GABRA1 (0.42) | GABRA1GABRB2SLC11A2GLASTING1 | |
| SCHEMBL10109859 | 0.86 | ALOX5 (0.58) | GABRA1GABRB2GLAALOX5AHR | |
| SCHEMBL16283943 | 0.85 | KMT2A (0.49) | SLC11A2KDM4EALDH1A1CTRCHTT | |
| SCHEMBL24819001 | 0.85 | ELANE (0.41) | GABRA1GABRB2SLC11A2GLASTING1 | |
| SCHEMBL12114639 | 0.85 | GABRA1 (0.39) | GABRA1GABRB2SLC11A2GLASTING1 | |
| SCHEMBL19779381 | 0.84 | PDCD1 (0.46) | GABRA1GABRB2SLC11A2GLASTING1 | |
| SCHEMBL21021446 | 0.81 | ALOX5 (0.38) | GABRA1GABRB2SLC11A2GLASTING1 | |
| SCHEMBL15842553 | 0.80 | KDM4E (0.53) | GABRA1GABRB2GLAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210004-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-06-29 | — | — | US | disclosed |
| US-20160181548-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160181548-A1 | MATERIALS FOR ELECTRONIC DEVICES | EPHB3, EPHA3, EPHB4 | GABRA1 2970/4885GABRB2 2408/4885SLC11A2 3544/4885 |
| US-20230210004-A1 | MATERIALS FOR ELECTRONIC DEVICES | EPHB3, EPHA3, EPHB4 | GABRA1 2970/4885GABRB2 2408/4885SLC11A2 3544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.