Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 5/20 | 0.34 |
| ▸ | CES2 | O00748 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895484 | 0.93 | ALDH1A1 (0.44) | ALDH1A1PAOXACHETDP1FFAR1 | |
| SCHEMBL1783764 | 0.86 | ALDH1A1 (0.43) | ALDH1A1PAOXACHETDP1CES1 | |
| SCHEMBL1782224 | 0.84 | ALDH1A1 (0.41) | ALDH1A1PAOXACHETDP1FFAR1 | |
| SCHEMBL8897386 | 0.83 | PAOX (0.45) | ALDH1A1PAOXTDP1FFAR1CPT2 | |
| SCHEMBL8896773 | 0.83 | CES1 (0.48) | ALDH1A1TDP1FFAR1CES1CES2 | |
| SCHEMBL27587027 | 0.83 | CES1 (0.48) | ALDH1A1TDP1FFAR1CES1CES2 | |
| SCHEMBL22500641 | 0.82 | AKR1B1 (0.52) | ALDH1A1TDP1FFAR1CPT2LMNA | |
| SCHEMBL1783727 | 0.82 | CES1 (0.39) | ALDH1A1TDP1FFAR1CPT2CES1 | |
| SCHEMBL8898733 | 0.82 | ALDH1A1 (0.41) | ALDH1A1PAOXACHETDP1CES1 | |
| SCHEMBL8899241 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TDP1FFAR1CPT2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | ALDH1A1 520/4885PAOX 2315/4885ACHE 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.