Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18371516 | 0.81 | PTGS1 (0.58) | PTGS1PTGS2ALDH1A1GAAMEN1 | |
| SCHEMBL2606133 | 0.80 | ALDH1A1 (0.37) | PTGS1PTGS2ALDH1A1GAAMEN1 | |
| SCHEMBL12285635 | 0.78 | PTGS1 (0.64) | PTGS1PTGS2ALDH1A1GAARAB9A | |
| SCHEMBL19038332 | 0.78 | SMN1; SMN2 (0.51) | PTGS1PTGS2ALDH1A1GAAMEN1 | |
| SCHEMBL25579885 | 0.78 | PTGS1 (0.64) | PTGS1PTGS2ALDH1A1GAARAB9A | |
| SCHEMBL14962678 | 0.78 | PTGS1 (0.64) | PTGS1PTGS2ALDH1A1GAARAB9A | |
| SCHEMBL21158479 | 0.77 | HDAC8 (0.41) | PTGS1PTGS2ALDH1A1GAAMEN1 | |
| SCHEMBL21158483 | 0.77 | HDAC8 (0.41) | PTGS1PTGS2ALDH1A1GAAMEN1 | |
| SCHEMBL21158478 | 0.77 | HDAC8 (0.41) | PTGS1PTGS2ALDH1A1GAAMEN1 | |
| SCHEMBL16283425 | 0.77 | HDAC8 (0.41) | PTGS1PTGS2ALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160193310-A1 | RM2 ANTIGENS AND USE THEREOF | ACADEMIA SINICA | 2016-07-07 | — | — | US | disclosed |
| US-20160175421-A1 | GLYCAN CONJUGATES AND USE THEREOF | WONG CHI-HUEY (US) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160175421-A1 | GLYCAN CONJUGATES AND USE THEREOF | FUT5, GNE, B3GNT2 | PTGS1 3656/4885PTGS2 3879/4885ALDH1A1 3542/4885 |
| US-20160193310-A1 | RM2 ANTIGENS AND USE THEREOF | LGALS2, MAN2B2, GALNT2 | PTGS1 4423/4885PTGS2 2172/4885ALDH1A1 3794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.