Desaspidin

Desaspidin

SCHEMBL29613713

CCCC(=O)C1=C(O)C(C)(C)C(O)=C(Cc2c(OC)cc(O)c(C(=O)CCC)c2O)C1=O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FASN P49327 8/20 0.51
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ PAK1 Q13153 1/20 0.42
▸ HMGCR P04035 1/20 0.35
▸ PTGES O14684 1/20 0.35
▸ ALOX5 P09917 1/20 0.35
▸ FFAR1 O14842 1/20 0.34
▸ PLA2G2A P14555 1/20 0.34
▸ PLA2G5 P39877 1/20 0.34
▸ CYP19A1 P11511 1/20 0.34
▸ MAPT P10636 1/20 0.33
▸ SENP8 Q96LD8 1/20 0.33
▸ SENP7 Q9BQF6 1/20 0.33
▸ SENP6 Q9GZR1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Desaspidin SCHEMBL2732746 1.00 FASN (0.51) FASNMEN1KMT2APAK1HMGCR
Desaspidin SCHEMBL28086151 0.90 FASN (0.42) FASNMEN1KMT2APAK1CYP19A1
SCHEMBL29387296 0.89 FASN (0.59) FASNMEN1KMT2APAK1HMGCR
SCHEMBL30212080 0.85 FASN (0.66) FASNMEN1KMT2APAK1HMGCR
SCHEMBL30212085 0.85 FASN (0.66) FASNMEN1KMT2APAK1HMGCR
SCHEMBL8573383 0.83 FASN (0.51) FASNMEN1KMT2APAK1HMGCR
SCHEMBL4742082 0.82 FASN (0.63) FASNPTGESALOX5
SCHEMBL155672 0.80 FASN (0.48) FASN
SCHEMBL1785484 0.78 FASN (0.60) FASNPTGESALOX5PLA2G2APLA2G5
SCHEMBL4962391 0.76 FASN (0.64) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12178790-B2 Antibacterial compound isolated from Psiloxylon mauritianum and its derivatives SORRES, Jonathan (FR) 2024-12-31 — — US disclosed
US-20230062900-A1 NEW ANTIBACTERIAL COMPOUND ISOLATED FROM PSILOXYLON MAURITIANUM AND ITS DERIVATIVES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2023-03-02 — — US disclosed
WO-2022097622-A1 ODOR ANALYZING DEVICE, ODOR ANALYSIS METHOD, AND ODOR ANALYSIS PROGRAM 株式会社レボーン 2022-05-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230062900-A1 NEW ANTIBACTERIAL COMPOUND ISOLATED FROM PSILOXYLON MAURITIANUM AND ITS DERIVATIVES PNN, AAAS, MRPS35 FASN 37/4885MEN1 2121/4885KMT2A 4246/4885
US-12178790-B2 Antibacterial compound isolated from Psiloxylon mauritianum and its derivatives AAAS, PNN, MRPL9 FASN 27/4885MEN1 1932/4885KMT2A 4078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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