Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 12/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9343840 | 0.82 | NPC1 (0.65) | NPC1KMT2ARAB9AMEN1MAPK1 | |
| SCHEMBL29365061 | 0.78 | NPC1 (0.55) | NPC1KMT2ARAB9AMEN1MAPK1 | |
| SCHEMBL397773 | 0.77 | MAPK1 (0.77) | NPC1KMT2ARAB9AMEN1MAPK1 | |
| SCHEMBL933959 | 0.77 | NPC1 (0.54) | NPC1KMT2ARAB9AMEN1MAPK1 | |
| SCHEMBL11291304 | 0.75 | NPC1 (0.53) | NPC1KMT2ARAB9AMEN1MAPK1 | |
| SCHEMBL11291307 | 0.75 | NPC1 (0.53) | NPC1KMT2ARAB9AMEN1MAPK1 | |
| SCHEMBL11910974 | 0.74 | MAPT (0.60) | NPC1KMT2ARAB9AMEN1MAPK1 | |
| SCHEMBL856759 | 0.74 | MAPK1 (0.60) | NPC1KMT2ARAB9AMEN1MAPK1 | |
| SCHEMBL950729 | 0.74 | MAPK1 (0.60) | NPC1KMT2ARAB9AMEN1MAPK1 | |
| SCHEMBL4793372 | 0.74 | MAPK1 (0.60) | NPC1KMT2ARAB9AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160178597-A1 | Systems and Methods Related to Optical Nanosensors Comprising Photoluminescent Nanostructures | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-06-23 | — | — | US | disclosed |