Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 11/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291304 | 1.00 | NPC1 (0.53) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL2003140 | 0.83 | RAB9A (0.58) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL9006320 | 0.83 | RAB9A (0.58) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL6129308 | 0.81 | RAB9A (0.55) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL7999930 | 0.81 | RAB9A (0.55) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL17855982 | 0.75 | NPC1 (0.58) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL9801440 | 0.74 | PLAU (0.56) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL9275769 | 0.73 | PLAU (0.59) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL9801446 | 0.73 | PLAU (0.59) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL13021483 | 0.73 | PLAU (0.55) | NPC1RAB9AKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013643-B1 | PRODUCTION OF HIGH-QUALITY AROMATIC AMINO AZO COMPOUNDS BY THE REARRANGEMENT OF 1,3-DIARYL TRIAZENES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-12-08 | — | — | EP | disclosed |
| US-4279815-A | DIAZOTIZATION, COUPLING | HERKES FRANK E | 1981-07-21 | — | — | US | disclosed |