Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 12/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17855982 | 0.77 | NPC1 (0.58) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL29365061 | 0.74 | NPC1 (0.55) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL397773 | 0.73 | MAPK1 (0.77) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL11291307 | 0.71 | NPC1 (0.53) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL11291304 | 0.71 | NPC1 (0.53) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL9343840 | 0.71 | NPC1 (0.65) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL11910974 | 0.70 | MAPT (0.60) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL973213 | 0.70 | MAPK1 (0.60) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL950729 | 0.70 | MAPK1 (0.60) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL373368 | 0.70 | MAPK1 (0.60) | NPC1KMT2ARAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106999632-B | Collagen sponge | 盖斯特里希医药公司 | 2018-03-20 | — | — | CN | disclosed |
| CN-106999632-A | Collagen sponge | 盖斯特里希医药公司 | 2017-08-01 | — | — | CN | disclosed |
| EP-2451981-A1 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | Somalogic, Inc. (US) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011006075-A1 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | SOMALOGIC, INC. (US) | 2011-01-13 | — | — | WO | disclosed |