Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 5/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | HRH2 | P25021 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19063564 | 0.91 | PTPN1 (0.67) | PTPN1PRMT1CHRM1CHRM3OPRK1 | |
| SCHEMBL17853018 | 0.91 | PTPN1 (0.59) | PTPN1PRMT1CHRM1CHRM3OPRK1 | |
| SCHEMBL17853016 | 0.91 | PTPN1 (0.59) | PTPN1PRMT1CHRM1CHRM3OPRK1 | |
| SCHEMBL29330707 | 0.89 | PTPN1 (0.57) | PTPN1PRMT1CHRM1CHRM3OPRK1 | |
| SCHEMBL19063553 | 0.87 | PTPN1 (0.62) | PTPN1PRMT1CHRM1CHRM3OPRK1 | |
| SCHEMBL19052122 | 0.87 | PTPN1 (0.61) | PTPN1PRMT1CHRM1CHRM3OPRK1 | |
| SCHEMBL29331243 | 0.86 | PTPN1 (0.60) | PTPN1PRMT1CHRM1CHRM3OPRK1 | |
| SCHEMBL17312257 | 0.86 | PTPN1 (0.63) | PTPN1PRMT1CHRM1CHRM3OPRK1 | |
| SCHEMBL17312269 | 0.86 | PTPN1 (0.63) | PTPN1PRMT1CHRM1CHRM3OPRK1 | |
| SCHEMBL17312268 | 0.86 | PTPN1 (0.63) | PTPN1PRMT1CHRM1CHRM3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160176819-A1 | ASYMMETRICALLY CHARGED NIR FLUOROPHORES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160176819-A1 | ASYMMETRICALLY CHARGED NIR FLUOROPHORES | CRY2, PARP15, CRY1 | PTPN1 4248/4885PRMT1 2539/4885CHRM1 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.