Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.54 |
| ▸ | PIK3C2B | O00750 | 16/20 | 0.54 |
| ▸ | MTOR | P42345 | 14/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19760618 | 0.93 | PIK3CD (0.64) | PIK3CDPIK3C2BMTORPIK3CGPIK3CB | |
| SCHEMBL19760561 | 0.92 | PIK3CD (0.66) | PIK3CDPIK3C2BMTORPIK3CGPIK3CB | |
| SCHEMBL17857348 | 0.87 | PIK3CD (0.65) | PIK3CDPIK3C2BMTORPIK3CGPIK3CB | |
| SCHEMBL17857345 | 0.86 | PIK3CD (0.51) | PIK3CDPIK3C2BMTORPIK3CGPIK3CB | |
| SCHEMBL19760551 | 0.81 | PIK3C2B (0.66) | PIK3CDPIK3C2BMTORPIK3CGPIK3CB | |
| SCHEMBL17857136 | 0.81 | PIK3C2B (0.61) | PIK3CDPIK3C2BMTORPIK3CGPIK3CB | |
| SCHEMBL19760603 | 0.81 | PIK3CD (0.55) | PIK3CDPIK3C2BMTORPIK3CGPIK3CB | |
| SCHEMBL19760540 | 0.80 | PIK3C2B (0.64) | PIK3CDPIK3C2BMTORPIK3CGPIK3CB | |
| SCHEMBL19760619 | 0.79 | PIK3CD (0.60) | PIK3CDPIK3C2BMTORPIK3CGPIK3CB | |
| SCHEMBL17857055 | 0.79 | PIK3CD (0.83) | PIK3CDPIK3C2BMTORPIK3CGPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016097347-A1 | IMIDAZOPYRIDAZINE DERIVATIVES AS ΡΙ3Κβ INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2016-06-23 | — | — | WO | disclosed |