Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | CHKA | P35790 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561470 | 0.92 | CHKA (0.59) | CHKAALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL4027686 | 0.90 | CHKA (0.57) | CHKAALDH1A1HSD17B10TP53HPGD | |
| Fluoride SCHEMBL27569609 | 0.88 | CHKA (0.56) | CHKAALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL31403228 | 0.87 | ALDH1A1 (0.56) | CHKAALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL27497441 | 0.86 | HTR1A (0.70) | HTR1AHTR7ALDH1A1HSD17B10TP53 | |
| SCHEMBL15033636 | 0.85 | CHKA (0.44) | HTR1AHTR7CHKAALDH1A1HSD17B10 | |
| Fluoride SCHEMBL27569600 | 0.85 | CHKA (0.53) | CHKAALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL11548897 | 0.82 | ALDH1A1 (0.58) | CHKAALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL13425929 | 0.82 | HTR1A (0.45) | HTR1AHTR7CHKAALDH1A1HSD17B10 | |
| SCHEMBL3892800 | 0.82 | NPC1 (0.50) | HTR1AHTR7CHKAALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375477-B2 | Topical compositions of aqueous gel type in the form of a homogeneous suspension of an active principle of the retinoid class containing at least one hydrophobic silica | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-28 | — | — | US | disclosed |