Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 18/20 | 0.49 |
| ▸ | IL1B | P01584 | 17/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17818726 | 0.84 | P2RX7 (0.66) | CNR1CNR2P2RX7IL1B | |
| SCHEMBL17818907 | 0.81 | P2RX7 (0.66) | CNR1CNR2P2RX7IL1B | |
| SCHEMBL17818957 | 0.78 | P2RX7 (0.64) | P2RX7IL1B | |
| SCHEMBL17818968 | 0.72 | P2RX7 (0.64) | CNR1CNR2P2RX7IL1B | |
| SCHEMBL28155873 | 0.71 | CNR1 (0.69) | CNR1CNR2P2RX7IL1B | |
| SCHEMBL17858310 | 0.70 | IL1B (0.67) | P2RX7IL1B | |
| SCHEMBL17858309 | 0.69 | IL1B (0.48) | CNR1CNR2P2RX7IL1B | |
| SCHEMBL17818776 | 0.69 | KDM4C (0.47) | CNR1CNR2P2RX7IL1B | |
| SCHEMBL17818838 | 0.69 | P2RX7 (0.65) | P2RX7IL1B | |
| SCHEMBL2994140 | 0.68 | CNR1 (0.51) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100281-A1 | INDOLE AND AZAINDOLES DERIVATIVES AND THEIR USE IN NEURODEGENERATIVE DISEASES | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | WO | disclosed |