Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17858986 | 0.88 | LRRK2 (0.60) | LRRK2NPC1RAB9APPARGPPARD | |
| SCHEMBL4490708 | 0.87 | RXFP1 (0.46) | LRRK2PPARGPPARDPPARANR1H4 | |
| SCHEMBL6103242 | 0.86 | LRRK2 (0.57) | LRRK2POLBSMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL17845904 | 0.86 | SMN1; SMN2 (0.53) | POLBSMN1; SMN2NPC1RAB9APPARA | |
| SCHEMBL3499940 | 0.86 | TRPV1 (0.53) | LRRK2SMN1; SMN2RXFP1ALDH1A1MAPT | |
| SCHEMBL17845895 | 0.86 | SMN1; SMN2 (0.52) | LRRK2POLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17859008 | 0.84 | SMN1; SMN2 (0.55) | LRRK2POLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6102385 | 0.84 | LRRK2 (0.52) | LRRK2POLBSMN1; SMN2PPARGPPARD | |
| SCHEMBL6101699 | 0.82 | LRRK2 (0.52) | LRRK2PPARGPPARDPPARANR1H4 | |
| SCHEMBL17845905 | 0.81 | SMN1; SMN2 (0.52) | POLBSMN1; SMN2NPC1RAB9APPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016095878-A1 | SUBSTITUTED DERIVATIVE OF OXYPHOSPHORUS ACIDS, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-23 | — | — | WO | disclosed |