Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845904 | 0.92 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ATLR8POLB | |
| SCHEMBL17859008 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ATLR8POLB | |
| SCHEMBL17845909 | 0.87 | P2RX1 (0.58) | SMN1; SMN2NPC1RAB9ATLR8POLB | |
| SCHEMBL17859072 | 0.86 | LRRK2 (0.52) | SMN1; SMN2NPC1RAB9APOLBMAPT | |
| SCHEMBL17845905 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9APOLBMAPT | |
| SCHEMBL17859065 | 0.81 | ALDH1A1 (0.49) | SMN1; SMN2NPC1RAB9APOLBMAPT | |
| SCHEMBL7515157 | 0.80 | ALDH1A1 (0.60) | SMN1; SMN2NPC1RAB9APOLBMAPT | |
| SCHEMBL17845884 | 0.76 | ALDH1A1 (0.53) | NPC1RAB9AMAPTALDH1A1HSD17B10 | |
| SCHEMBL17845889 | 0.75 | TMPRSS4 (0.61) | SMN1; SMN2NPC1RAB9ATLR8POLB | |
| SCHEMBL6103242 | 0.75 | LRRK2 (0.57) | SMN1; SMN2POLBMAPTALDH1A1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016095878-A1 | SUBSTITUTED DERIVATIVE OF OXYPHOSPHORUS ACIDS, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-23 | — | — | WO | disclosed |