Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845904 | 0.91 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TMPRSS4MAPTGFER | |
| SCHEMBL17859008 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1TMPRSS4MAPTGFER | |
| SCHEMBL17845895 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1TMPRSS4MAPTGFER | |
| SCHEMBL6099647 | 0.84 | TMPRSS4 (0.50) | SMN1; SMN2TMPRSS4MAPTPOLBNPSR1 | |
| SCHEMBL3499720 | 0.83 | TMPRSS4 (0.54) | SMN1; SMN2ALDH1A1TMPRSS4MAPTGFER | |
| SCHEMBL3497252 | 0.83 | TRPV1 (0.57) | SMN1; SMN2ALDH1A1TMPRSS4MAPTPOLB | |
| SCHEMBL17859072 | 0.81 | LRRK2 (0.52) | SMN1; SMN2ALDH1A1MAPTGFERHSD17B10 | |
| SCHEMBL3496634 | 0.81 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1TMPRSS4MAPTGFER | |
| SCHEMBL17845892 | 0.79 | TMPRSS4 (0.80) | SMN1; SMN2TMPRSS4P2RX1P2RX4P2RX7 | |
| SCHEMBL3853307 | 0.79 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1TMPRSS4MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016095878-A1 | SUBSTITUTED DERIVATIVE OF OXYPHOSPHORUS ACIDS, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-23 | — | — | WO | disclosed |