SCHEMBL1785935

SCHEMBL1785935

CCC(C)(C)C(OC(=O)c1ccccc1)C(C)(C)OC(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
TSHR P16473 3/20 0.44
TP53 P04637 1/20 0.44
ALDH1A1 P00352 4/20 0.41
LMNA P02545 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
HSD17B10 Q99714 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
HTR1A P08908 1/20 0.40
SCN1A P35498 1/20 0.40
SLC6A3 Q01959 1/20 0.40
SCN5A Q14524 1/20 0.40
SCN2A Q99250 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1783893 0.84 KMT2A (0.49) CYP2D6CYP1A2CYP2C19KMT2AMEN1
SCHEMBL1784502 0.80 CYP2D6 (0.54) CYP2D6CYP1A2CYP2C19KMT2AMEN1
SCHEMBL6721673 0.80 MEN1 (0.51) CYP2D6CYP1A2CYP2C19KMT2AMEN1
SCHEMBL1784530 0.78 CYP2D6 (0.51) CYP2D6CYP1A2CYP2C19KMT2AMEN1
SCHEMBL1782189 0.77 CYP2D6 (0.47) CYP2D6CYP1A2CYP2C19KMT2AMEN1
SCHEMBL1788323 0.76 TSHR (0.50) CYP2D6CYP1A2CYP2C19KMT2AMEN1
SCHEMBL18671496 0.76 MAPK1 (0.47) CYP2D6CYP1A2CYP2C19KMT2AMEN1
SCHEMBL1787176 0.76 KMT2A (0.50) CYP2D6CYP1A2CYP2C19KMT2AMEN1
SCHEMBL28970002 0.76 CYP2D6 (0.54) CYP2D6CYP1A2CYP2C19KMT2AMEN1
SCHEMBL1334578 0.75 CYP2D6 (0.49) CYP2D6CYP1A2CYP2C19KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US claimed
EP-3486263-A2 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE W.R. Grace & CO. - CONN. (US) 2019-05-22 EP disclosed
EP-2185600-B1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE GRACE W R & CO (US) 2018-10-31 EP disclosed
US-9796796-B2 Self-limiting catalyst composition with No silane W. R. GRACE & CO.-CONN. (US) 2017-10-24 US disclosed
EP-1666505-B1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2016-03-23 EP disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110124491-A1 Self-Limiting Catalyst Composition with No Silane W. R. GRACE & CO.-CONN. 2011-05-26 US disclosed
EP-1713843-B1 METHOD FOR GRAFTING A FLUORINATED POLYMER, AND MULTILAYER STRUCTURES COMPRISING SAID GRAFTED POLYMER ARKEMA FRANCE (FR) 2008-12-03 EP disclosed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US disclosed
US-7332455-B2 Catalyst component and catalyst for olefin polymerization as well as use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-02-19 US disclosed
EP-1713843-A1 METHOD FOR GRAFTING A FLUORINATED POLYMER, AND MULTILAYER STRUCTURES COMPRISING SAID GRAFTED POLYMER Arkema France (FR) 2006-10-25 EP disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US disclosed
WO-2005068522-A1 METHOD FOR GRAFTING A FLUORINATED POLYMER, AND MULTILAYER STRUCTURES COMPRISING SAID GRAFTED POLYMER ARKEMA FRANCE (FR) 2005-07-28 WO disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed