Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | G6PD | P11413 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29660514 | 0.86 | KDM4E (0.64) | ALDH1A1LMNAKDM4EMEN1GAA | |
| SCHEMBL206362 | 0.86 | KDM4E (0.64) | ALDH1A1LMNAKDM4EMEN1GAA | |
| SCHEMBL6287527 | 0.83 | KDM4E (0.52) | ALDH1A1LMNAKDM4EMEN1GAA | |
| SCHEMBL31533497 | 0.83 | KDM4E (0.56) | ALDH1A1LMNAKDM4EMEN1GAA | |
| SCHEMBL27343976 | 0.83 | ALDH1A1 (0.56) | ALDH1A1LMNAKDM4EMEN1GAA | |
| SCHEMBL24498386 | 0.79 | KDM4E (0.51) | ALDH1A1LMNAKDM4EMEN1GAA | |
| SCHEMBL29186553 | 0.79 | KDM4E (0.47) | ALDH1A1LMNAKDM4EMEN1GAA | |
| SCHEMBL9049314 | 0.79 | LMNA (0.51) | ALDH1A1LMNAKDM4EMEN1GAA | |
| SCHEMBL4341886 | 0.78 | MAPK1 (0.67) | ALDH1A1LMNAKDM4EMEN1GAA | |
| SCHEMBL16879974 | 0.77 | KDM4E (1.00) | ALDH1A1LMNAKDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11155969-B2 | Polystyrene-based structural materials | GAINES DANIEL P (US) | 2021-10-26 | — | — | US | disclosed |
| US-20180313041-A1 | Polystyrene-Based Structural Materials | GAINES DANIEL P (US) | 2018-11-01 | — | — | US | disclosed |
| WO-2018045387-A1 | POLYMER NANOPARTICLE THERMAL INSULATORS | NanoSD Inc. (US) | 2018-03-08 | — | — | WO | disclosed |
| US-20180066131-A1 | POLYMER NANOPARTICLE THERMAL INSULATORS | NanoSD Inc. | 2018-03-08 | — | — | US | disclosed |
| US-8592430-B2 | Quinazolin-oxime derivatives as Hsp90 inhibitors | DAC SLR (IT) | 2013-11-26 | — | — | US | disclosed |
| WO-2013064919-A1 | QUINAZOLINE DERIVATIVES WITH HSP90 INHIBITORY ACTIVITY | DAC SRL (IT) | 2013-05-10 | — | — | WO | disclosed |
| EP-2144889-B1 | QUINAZOLIN-OXIME DERIVATIVES AS HSP90 INHIBITORS | DAC SRL (IT) | 2012-08-29 | — | — | EP | disclosed |
| US-20110118258-A1 | QUINAZOLIN-OXIME DERIVATIVES AS HSP90 INHIBITORS | DAC SRL (IT) | 2011-05-19 | — | — | US | disclosed |
| EP-2144889-A2 | QUINAZOLIN-OXIME DERIVATIVES AS HSP90 INHIBITORS | DAC S.r.l. (IT) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008142720-A2 | QUINAZOLIN-OXIME DERIVATIVES AS HSP90 INHIBITORS | DAC SRL (IT) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118258-A1 | QUINAZOLIN-OXIME DERIVATIVES AS HSP90 INHIBITORS | HSP90AB1, HSP90AA1, HSP90B1 | ALDH1A1 1998/4885LMNA 4565/4885KDM4E 2835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.