Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.42 |
| ▸ | DNPH1 | O43598 | 4/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 3/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18310607 | 0.98 | P2RY12 (0.42) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL17860533 | 0.92 | P2RY12 (0.39) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL17860584 | 0.91 | P2RY12 (0.39) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL20341134 | 0.91 | P2RY12 (0.39) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL20341104 | 0.91 | P2RY12 (0.41) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL18310603 | 0.91 | P2RY12 (0.37) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL18310609 | 0.89 | P2RY12 (0.37) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL17860551 | 0.88 | P2RY12 (0.38) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL25628723 | 0.87 | TYMP (0.38) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL24209112 | 0.87 | TYMP (0.38) | P2RY12DNPH1P2RY2P2RY1P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667664-B2 | Cyclic dinucleotides for cytokine induction | KAYLA THERAPEUTICS (FR) | 2023-06-06 | — | — | US | disclosed |
| US-11667664-B2 | Cyclic dinucleotides for cytokine induction | KAYLA THERAPEUTICS (FR) | 2023-06-06 | — | — | US | disclosed |
| US-20220017561-A1 | CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION | KAYLA THERAPEUTICS (FR) | 2022-01-20 | — | — | US | disclosed |
| US-11053272-B2 | Cyclic dinucleotides for cytokine induction | KAYLA THERAPEUTICS (FR) | 2021-07-06 | — | — | US | disclosed |
| US-20200255469-A1 | CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION | KAYLA THERAPEUTICS (FR) | 2020-08-13 | — | — | US | disclosed |
| US-10562929-B2 | Cyclic dinucleotides for cytokine induction | KAYLA THERAPEUTICS (FR) | 2020-02-18 | — | — | US | disclosed |
| US-10011630-B2 | Cyclic dinucleotides for cytokine induction | INVIVOGEN (FR) | 2018-07-03 | — | — | US | disclosed |
| US-10011630-B2 | Cyclic dinucleotides for cytokine induction | INVIVOGEN (FR) | 2018-07-03 | — | — | US | disclosed |
| US-20160362441-A1 | CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION | KAYLA THERAPEUTICS (FR) | 2016-12-15 | — | — | US | disclosed |
| US-20160362441-A1 | CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION | KAYLA THERAPEUTICS (FR) | 2016-12-15 | — | — | US | disclosed |
| WO-2016096174-A1 | FLUORINATED CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION | INVIVOGEN (FR) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160362441-A1 | CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION | IL1B, IFNG, IFNAR1 | P2RY12 908/4885DNPH1 2540/4885P2RY2 911/4885 |
| US-11053272-B2 | Cyclic dinucleotides for cytokine induction | IL1B, IFNG, IFNAR1 | P2RY12 908/4885DNPH1 2540/4885P2RY2 911/4885 |
| US-20200255469-A1 | CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION | IL1B, IFNG, IFNAR1 | P2RY12 908/4885DNPH1 2540/4885P2RY2 911/4885 |
| US-10011630-B2 | Cyclic dinucleotides for cytokine induction | IL1B, IFNG, IFNAR1 | P2RY12 908/4885DNPH1 2540/4885P2RY2 911/4885 |
| US-20220017561-A1 | CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION | IL1B, IFNG, IFNAR1 | P2RY12 908/4885DNPH1 2540/4885P2RY2 911/4885 |
| US-11667664-B2 | Cyclic dinucleotides for cytokine induction | IL1B, IFNG, IFNAR1 | P2RY12 908/4885DNPH1 2540/4885P2RY2 911/4885 |
| US-10562929-B2 | Cyclic dinucleotides for cytokine induction | IL1B, IFNG, IFNAR1 | P2RY12 908/4885DNPH1 2540/4885P2RY2 911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.