Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17860717 | 0.89 | LMNA (0.41) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL1713745 | 0.88 | FAAH (0.54) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL3707005 | 0.86 | LMNA (0.57) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL10900230 | 0.86 | FAAH (0.53) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL2449155 | 0.86 | LMNA (0.62) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL11386694 | 0.86 | LMNA (0.57) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL6673131 | 0.85 | LMNA (0.66) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL10029403 | 0.85 | FAAH (0.51) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL8421692 | 0.85 | LMNA (0.66) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL18188008 | 0.83 | LMNA (0.69) | FAAHCNR1CNR2LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100578-A2 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |