Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16826935 | 0.88 | ALDH1A1 (0.54) | ALDH1A1ATMTSHRHPGDNPSR1 | |
| SCHEMBL6738625 | 0.86 | ALDH1A1 (0.48) | ALDH1A1ATMTSHRHPGDNPSR1 | |
| SCHEMBL1471817 | 0.86 | ALDH1A1 (0.52) | ALDH1A1ATMTSHRHPGDNPSR1 | |
| SCHEMBL18859460 | 0.86 | ALDH1A1 (0.52) | ALDH1A1ATMTSHRHPGDNPSR1 | |
| SCHEMBL6234940 | 0.86 | ALDH1A1 (0.52) | ALDH1A1ATMTSHRHPGDNPSR1 | |
| SCHEMBL5458029 | 0.86 | ALDH1A1 (0.52) | ALDH1A1ATMTSHRHPGDNPSR1 | |
| SCHEMBL7219469 | 0.84 | CA1 (0.55) | ALDH1A1ATMTSHRHPGDMAPT | |
| SCHEMBL17860723 | 0.84 | ALDH1A1 (0.50) | ALDH1A1ATMTSHRHPGDNPSR1 | |
| SCHEMBL3682422 | 0.82 | CA1 (0.53) | ALDH1A1ATMTSHRMAPTCA1 | |
| SCHEMBL17211387 | 0.82 | ALDH1A1 (0.48) | ALDH1A1ATMTSHRHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100578-A2 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |