Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17882068 | 0.82 | MEN1 (0.33) | MEN1KMT2ALPAR3LPAR1LPAR2 | |
| SCHEMBL17878615 | 0.77 | MEN1 (0.34) | MEN1KMT2AHMGCR | |
| SCHEMBL12044584 | 0.73 | MEN1 (0.39) | MEN1KMT2ALPAR3LPAR1LPAR2 | |
| SCHEMBL17860890 | 0.71 | CYP3A4 (0.48) | LPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL3899262 | 0.69 | MEN1 (0.37) | MEN1KMT2ALPAR3LPAR1LPAR2 | |
| SCHEMBL17860873 | 0.69 | LMNA (0.33) | MEN1KMT2ALPAR3LPAR1LPAR2 | |
| SCHEMBL19114950 | 0.68 | CYP3A4 (0.39) | MEN1KMT2ALPAR3LPAR1LPAR2 | |
| SCHEMBL24593983 | 0.68 | CYP3A4 (0.45) | LPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL17878603 | 0.67 | CYP3A4 (0.44) | MEN1KMT2ALPAR3LPAR1LPAR2 | |
| SCHEMBL11431291 | 0.67 | DGAT1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100578-A2 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |