SCHEMBL178622

SCHEMBL178622

CNC(C)Cc1ccc(OC)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.60
TAAR1 Q96RJ0 2/20 0.59
SIGMAR1 Q99720 2/20 0.59
SLC18A2 Q05940 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.55
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
ACACB O00763 1/20 0.53
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C19 P33261 1/20 0.52
LDHA P00338 1/20 0.52
ADRB2 P07550 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL896368 1.00 SLC6A4 (0.60) SLC6A4TAAR1SIGMAR1SLC18A2L3MBTL1
Hydrochloric Acid SCHEMBL29410112 0.98 SLC6A4 (0.58) SLC6A4TAAR1SIGMAR1SLC18A2L3MBTL1
SCHEMBL24105648 0.84 SLC6A4 (0.66) SLC6A4SIGMAR1L3MBTL1MEN1KMT2A
SCHEMBL25890567 0.84 SLC6A4 (0.66) SLC6A4SIGMAR1L3MBTL1MEN1KMT2A
SCHEMBL4380664 0.83 TAAR1 (0.49) SLC6A4TAAR1SIGMAR1SLC18A2MEN1
SCHEMBL10395444 0.82 SLC6A4 (0.63) SLC6A4SIGMAR1L3MBTL1MEN1KMT2A
SCHEMBL2958349 0.82 SLC6A4 (0.58) SLC6A4SIGMAR1L3MBTL1MEN1KMT2A
SCHEMBL21089970 0.82 CYP1A2 (0.61) SLC6A4SIGMAR1L3MBTL1MEN1KMT2A
SCHEMBL16383872 0.82 SLC6A4 (0.58) SLC6A4SIGMAR1L3MBTL1MEN1KMT2A
SCHEMBL3341789 0.81 SIGMAR1 (0.61) SLC6A4SIGMAR1L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250130211-A1 METHOD OF SCREENING NEW PSYCHOACTIVE SUBSTANCE AND PLATFORM THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2025-04-24 US claimed
CN-117504833-B Mixed mode weak cation exchange magnetic solid phase extraction adsorbent and preparation method and application thereof 浙江警察学院 2025-03-28 CN claimed
CN-114965780-B Method for simultaneously measuring 30 mental active substances in environmental water body 中科检测技术服务(广州)股份有限公司 2024-09-24 CN claimed
CN-118443818-A Silanized polydopamine modified membrane, preparation method thereof and application thereof in amphetamine drugs and metabolite detection 华南理工大学 2024-08-06 CN claimed
CN-115948936-B Extraction paper, preparation method thereof and application of extraction paper in amphetamine drugs detection 中科检测技术服务(广州)股份有限公司 2024-01-26 CN claimed
CN-115948936-A Extraction paper, preparation method thereof and application of extraction paper in detection of amphetamine drugs 中科检测技术服务(广州)股份有限公司 2023-04-11 CN claimed
US-10700282-B2 Synthesis and incorporation of graphene and/or metallized or metal oxide-modified graphene to improve organic solar cells and hydrogen fuel cells THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2020-06-30 US claimed
US-20190189924-A9 SYNTHESIS AND INCORPORATION OF GRAPHENE AND/OR METALLIZED OR METAL OXIDE-MODIFIED GRAPHENE TO IMPROVE ORGANIC SOLAR CELLS AND HYDROGEN FUEL CELLS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK 2019-06-20 US claimed
US-20170179393-A1 SYNTHESIS AND INCORPORATION OF GRAPHENE AND/OR METALLIZED OR METAL OXIDE-MODIFIED GRAPHENE TO IMPROVE ORGANIC SOLAR CELLS AND HYDROGEN FUEL CELLS UNIV NEW YORK STATE RES FOUND (US) 2017-06-22 US claimed
US-9435816-B2 Deuterium free, stable isotope labeled 2-phenylethylamine hallucinogens and/or stimulants, methods of their preparation and their use CHIRON AS (NO) 2016-09-06 US claimed
WO-2015143353-A1 SYNTHESIS AND INCORPORATION OF GRAPHENE AND/OR METALLIZED OR METAL OXIDE-MODIFIED GRAPHENE TO IMPROVE ORGANIC SOLAR CELLS AND HYDROGEN FUEL CELLS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2015-09-24 WO claimed
US-20140227792-A1 DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE CHIRON A/S (NO) 2014-08-14 US claimed
WO-2013014287-A2 DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE CHIRON AS (NO) 2013-01-31 WO claimed
EP-2551675-A1 Deuterium free, stable isotope labeled 2-phenylethylamine hallucinogens and/or stimulants, methods fo their preparation and their use Chiron AS (NO) 2013-01-30 EP claimed
US-20080157427-A1 METHOD FOR FABRICATING MICRONEEDLE ARRAY AND METHOD FOR FABRICATING EMBOSSING MOLD OF MICRONEEDLE ARRAY NATIONAL CHIAO TUNG UNIVERSITY (TW) 2008-07-03 US claimed
CN-122046000-A Garbage classification method integrating Raman spectrum detection and pyrolysis high-valued treatment 华中科技大学 2026-05-15 CN disclosed
EP-3841085-B1 NBOME TEST UNIV SYDNEY TECHNOLOGY (AU) 2026-05-06 EP disclosed
US-20080157427-A1 METHOD FOR FABRICATING MICRONEEDLE ARRAY AND METHOD FOR FABRICATING EMBOSSING MOLD OF MICRONEEDLE ARRAY NATIONAL CHIAO TUNG UNIVERSITY (TW) 2008-07-03 US disclosed
WO-2007016190-A2 ANTIPARKINSONIAN ACTION OF PHENYLISOPROPYLAMINES DUKE UNIVERSITY (US) 2007-02-08 WO disclosed
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140227792-A1 DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE PNMT, HTR2C, HTR2A SLC6A4 50/4885TAAR1 16/4885SIGMAR1 66/4885
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines PNMT, SNCA, COMT SLC6A4 178/4885TAAR1 1075/4885SIGMAR1 188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.