SCHEMBL17864151

SCHEMBL17864151

c1ccc2c(-c3nc(-n4c5ccccc5c5ccc6c7ccc8ccccc8c7ccc6c54)nc4ccccc34)cccc2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
HPGD P15428 4/20 0.36
KDM4E B2RXH2 4/20 0.36
MAPT P10636 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
DUSP3 P51452 1/20 0.36
HPRT1 P00492 1/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
ADORA2A P29274 3/20 0.34
TDP1 Q9NUW8 1/20 0.34
LMNA P02545 1/20 0.34
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34
TUBB4B P68371 1/20 0.34
TUBB3 Q13509 1/20 0.34
TUBB2A Q13885 1/20 0.34
TUBB8 Q3ZCM7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24104188 0.96 ALDH1A1 (0.37) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL17864189 0.93 ALDH1A1 (0.33) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL17864184 0.91 ALDH1A1 (0.41) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL19359934 0.89 KDM4E (0.41) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL12014852 0.88 ALDH1A1 (0.42) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL17864177 0.87 ALDH1A1 (0.50) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL19961621 0.87 KDM4E (0.31) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL21168940 0.87 KDM4E (0.38) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL19979401 0.86 KDM4E (0.38) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL17864101 0.86 TUBB4A (0.34) ALDH1A1HPGDKDM4EMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016099037-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2016-06-23 WO disclosed