SCHEMBL17864183

SCHEMBL17864183

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccccc4c4cc(-n5c6ccccc6c6ccc7ccc8c9ccccc9ccc8c7c65)ccc43)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAC2 P15153 1/20 0.34
RAC3 P60763 1/20 0.34
CDC42 P60953 1/20 0.34
RAC1 P63000 1/20 0.34
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
RECQL P46063 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ERBB2 P04626 1/20 0.31
CYP1A2 P05177 1/20 0.31
FYN P06241 1/20 0.31
MAOA P21397 1/20 0.31
ACHE P22303 1/20 0.31
AHR P35869 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HPRT1 P00492 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17864188 0.93 RAC2 (0.36) RAC2RAC3CDC42RAC1NPC1
SCHEMBL17864112 0.89 RAC2 (0.35) RAC2RAC3CDC42RAC1NPC1
SCHEMBL17864164 0.89 MAPT (0.38) NPC1LMNAMAPTRECQLRAB9A
SCHEMBL17864182 0.88 KDM4E (0.36) NPC1LMNAMAPTRECQLRAB9A
SCHEMBL20315814 0.86 RAC2 (0.34) RAC2RAC3CDC42RAC1KDM4E
SCHEMBL22884221 0.86 RAC2 (0.34) RAC2RAC3CDC42RAC1NPC1
SCHEMBL15801888 0.85 RAC2 (0.32) RAC2RAC3CDC42RAC1KDM4E
SCHEMBL15606678 0.85 L3MBTL1 (0.37) RAC2RAC3CDC42RAC1NPC1
SCHEMBL12033899 0.85 L3MBTL1 (0.42) RAC2RAC3CDC42RAC1NPC1
SCHEMBL17864173 0.85 KDM4E (0.46) ERBB2CYP1A2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016099037-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2016-06-23 WO disclosed