SCHEMBL17865121

SCHEMBL17865121

FC(F)(F)CC1CN(c2nccc3ccccc23)CCN1

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.55
HRH4 Q9H3N8 1/20 0.46
SORD Q00796 2/20 0.42
DPP4 P27487 2/20 0.42
DPP7 Q9UHL4 1/20 0.42
GRM4 Q14833 3/20 0.37
PRKCQ Q04759 1/20 0.37
PRKCD Q05655 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6281370 0.79 HTR2C (0.65) HTR2CHRH4SORDDPP4PRKCQ
SCHEMBL6271843 0.79 HTR2C (0.65) HTR2CHRH4SORDDPP4PRKCQ
SCHEMBL2076366 0.72 HTR2C (1.00) HTR2CHRH4SORD
SCHEMBL30040877 0.72 HTR2C (1.00) HTR2CHRH4SORD
SCHEMBL17865120 0.72 HRH4 (0.46) HTR2CHRH4SORDDPP4DPP7
Hydrochloric Acid SCHEMBL1532881 0.71 HTR2C (0.97) HTR2CHRH4SORD
SCHEMBL17844907 0.70 HTR2C (0.53) HTR2CHRH4SORDDPP4DPP7
SCHEMBL30534241 0.69 SCD (0.39) PRKCQPRKCD
SCHEMBL9881973 0.69 PRKCQ (0.55) PRKCQPRKCD
SCHEMBL30614541 0.68 HRH4 (0.56) HTR2CHRH4SORDDPP4DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10369130-B2 Antibacterial compounds AZIEN DE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. (IT) 2019-08-06 US disclosed
WO-2016096631-A1 NEW ANTIBACTERIAL COMPOUNDS AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 2016-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10369130-B2 Antibacterial compounds MRPL21, CLPP, NRDC HTR2C 4816/4885HRH4 3610/4885SORD 1360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.