Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.57 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | SORD | Q00796 | 2/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271843 | 1.00 | HTR2C (0.65) | HTR2CHRH4KITSORDPRKCQ | |
| SCHEMBL3680688 | 0.80 | NCF1 (0.49) | HTR2CKITNCF1 | |
| SCHEMBL17844907 | 0.80 | HTR2C (0.53) | HTR2CHRH4SORDACACBPHGDH | |
| SCHEMBL2076366 | 0.79 | HTR2C (1.00) | HTR2CHRH4SORDADRB2NCF1 | |
| SCHEMBL30040877 | 0.79 | HTR2C (1.00) | HTR2CHRH4SORDADRB2NCF1 | |
| SCHEMBL17865121 | 0.79 | HTR2C (0.55) | HTR2CHRH4SORDPRKCQPRKCD | |
| Hydrochloric Acid SCHEMBL1532881 | 0.78 | HTR2C (0.97) | HTR2CHRH4SORDADRB2NCF1 | |
| SCHEMBL2797038 | 0.78 | LMNA (0.60) | HRH4KITADRA2AADRA2BADRA2C | |
| SCHEMBL13595594 | 0.78 | NCF1 (0.65) | HTR2CKITPRKCQPRKCDKHK | |
| SCHEMBL3683893 | 0.77 | HTR2C (0.47) | HTR2CHRH4KITPRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121094-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES AS ANTI-HIV-AGENTS | PFIZER LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |