SCHEMBL17865367

SCHEMBL17865367

CC(O)[n+]1ccn(C)c1CO.COC(=O)[O-]

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
APOBEC3A P31941 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17865368 0.67 KDM4E (0.40) KDM4EAPOBEC3ASMN1; SMN2APOBEC3G
SCHEMBL2699540 0.64 HDAC8 (0.43) KDM4EAPOBEC3ASMN1; SMN2APOBEC3G
SCHEMBL486838 0.64 KDM4E (0.33) KDM4EAPOBEC3ASMN1; SMN2APOBEC3G
Hydrochloric Acid SCHEMBL28497573 0.62 HDAC8 (0.31)
SCHEMBL21049612 0.62
SCHEMBL22832298 0.61 CA1 (0.43) KDM4EAPOBEC3ASMN1; SMN2APOBEC3G
SCHEMBL28437944 0.61
SCHEMBL17438922 0.59 ALDH1A1 (0.41) SMN1; SMN2
L-Lactic Acid SCHEMBL1331540 0.57 CA1 (0.31)
SCHEMBL1900632 0.56 MEN1 (0.32) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3037889-B1 MEMBER FOR ELECTROPHOTOGRAPHY AND METHOD OF PRODUCING THE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2023-11-29 EP disclosed
US-10108129-B2 Member for electrophotography and method of producing the member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2018-10-23 US disclosed
US-20160187809-A1 MEMBER FOR ELECTROPHOTOGRAPHY AND METHOD OF PRODUCING THE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-06-30 US disclosed
EP-3037889-A1 MEMBER FOR ELECTROPHOTOGRAPHY AND METHOD OF PRODUCING THE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS Canon Kabushiki Kaisha (JP) 2016-06-29 EP disclosed