SCHEMBL17865368

SCHEMBL17865368

COC(=O)[O-].C[n+]1ccn(CCO)c1CO

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
APOBEC3A P31941 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
HTT P42858 1/20 0.31
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21490417 0.74 CA1 (0.38) KDM4EAPOBEC3ASMN1; SMN2APOBEC3GCA1
SCHEMBL486840 0.71 ACHE (0.40) KDM4EAPOBEC3ASMN1; SMN2APOBEC3GCA1
Hydrochloric Acid SCHEMBL17906574 0.70 KMT2A (0.40) KDM4EAPOBEC3ASMN1; SMN2APOBEC3GCA1
SCHEMBL22832299 0.70 CA1 (0.40) KDM4EAPOBEC3ASMN1; SMN2APOBEC3GCA1
SCHEMBL2699540 0.68 HDAC8 (0.43) KDM4EAPOBEC3ASMN1; SMN2APOBEC3GHTT
SCHEMBL17865367 0.67 KDM4E (0.36) KDM4EAPOBEC3ASMN1; SMN2APOBEC3G
SCHEMBL666878 0.67 CA1 (0.51) APOBEC3AAPOBEC3GCA1CA2HDAC8
Hydrochloric Acid SCHEMBL15318972 0.65 CA1 (0.50) CA1CA2HDAC8
SCHEMBL21049579 0.64 KDM4E (0.33) KDM4EAPOBEC3ASMN1; SMN2APOBEC3GHDAC8
SCHEMBL2229764 0.62 SMN1; SMN2 (0.50) SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3037889-B1 MEMBER FOR ELECTROPHOTOGRAPHY AND METHOD OF PRODUCING THE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2023-11-29 EP disclosed
US-10108129-B2 Member for electrophotography and method of producing the member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2018-10-23 US disclosed
US-20160187809-A1 MEMBER FOR ELECTROPHOTOGRAPHY AND METHOD OF PRODUCING THE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-06-30 US disclosed
EP-3037889-A1 MEMBER FOR ELECTROPHOTOGRAPHY AND METHOD OF PRODUCING THE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS Canon Kabushiki Kaisha (JP) 2016-06-29 EP disclosed