SCHEMBL17865780

SCHEMBL17865780

CC(C)(C)CCNC(=O)c1ccc(C(=O)NCCC(C)(C)C)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.77
NAMPT P43490 2/20 0.57
NPC1 O15118 4/20 0.54
RAB9A P51151 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
MAPK1 P28482 2/20 0.54
TP53 P04637 1/20 0.54
HPGD P15428 1/20 0.54
NFKB1 P19838 1/20 0.54
NFKB2 Q00653 1/20 0.54
RELA Q04206 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ALDH1A1 P00352 2/20 0.53
LMNA P02545 2/20 0.52
POLB P06746 1/20 0.52
ESRRB O95718 1/20 0.50
ESRRG P62508 1/20 0.50
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12243059 0.93 MLYCD (0.69) MLYCDNPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL5687748 0.93 MLYCD (0.69) MLYCDNAMPTNPC1RAB9ASMN1; SMN2
SCHEMBL19938019 0.91 MLYCD (0.67) MLYCDNAMPTNPC1RAB9ASMN1; SMN2
SCHEMBL7213166 0.91 MLYCD (0.71) MLYCDNAMPTNPC1RAB9AL3MBTL1
SCHEMBL10224050 0.90 MLYCD (0.66) MLYCDNAMPTNPC1RAB9ASMN1; SMN2
SCHEMBL9784573 0.89 MLYCD (0.65) MLYCDNAMPTNPC1RAB9ASMN1; SMN2
SCHEMBL24610430 0.88 MLYCD (0.63) MLYCDNAMPTNPC1RAB9ASMN1; SMN2
SCHEMBL8160658 0.88 NPC1 (0.63) MLYCDNAMPTNPC1RAB9ASMN1; SMN2
SCHEMBL4046112 0.87 MLYCD (0.62) MLYCDNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL7219286 0.87 MLYCD (0.61) MLYCDNAMPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475085-B1 MULTILAYER FILMS AND PACKAGES FORMED FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2023-07-05 EP disclosed
CN-109195795-B Multilayer film and package formed therefrom 陶氏环球技术有限责任公司 2022-02-18 CN disclosed
EP-3237521-B1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-27 EP disclosed
EP-3237521-B1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-27 EP disclosed
US-10316168-B2 Polyethylene compositions with improved optical properties DOW GLOBAL TECHNOLOGIES LLC (US) 2019-06-11 US disclosed
US-10316168-B2 Polyethylene compositions with improved optical properties DOW GLOBAL TECHNOLOGIES LLC (US) 2019-06-11 US disclosed
EP-3475085-A1 MULTILAYER FILMS AND PACKAGES FORMED FROM SAME Dow Global Technologies LLC (US) 2019-05-01 EP disclosed
US-20190118516-A1 MULTILAYER FILMS AND PACKAGES FORMED FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-25 US disclosed
US-20190118516-A1 MULTILAYER FILMS AND PACKAGES FORMED FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-25 US disclosed
US-20180022894-A1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-01-25 US disclosed
US-20180022894-A1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-01-25 US disclosed
US-20180022894-A1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-01-25 US disclosed
EP-3260295-A1 MULTILAYER FILMS AND PACKAGES FORMED FROM SAME Dow Global Technologies LLC (US) 2017-12-27 EP disclosed
EP-3237521-A1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES Dow Global Technologies LLC (US) 2017-11-01 EP disclosed
WO-2016105610-A1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES DOW GLOBAL TECHNOLOGIES LLC (US) 2016-06-30 WO disclosed
EP-3037466-A1 Polyethylene compositions with improved optical properties Dow Global Technologies LLC (US) 2016-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180022894-A1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES PARG, PARN, FHIT MLYCD 4456/4885NAMPT 658/4885NPC1 1656/4885
US-10316168-B2 Polyethylene compositions with improved optical properties PARG, PARN, FHIT MLYCD 4456/4885NAMPT 658/4885NPC1 1656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.