Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865892 | 0.90 | L3MBTL1 (0.43) | TP53KDM4EVNN1L3MBTL1LMNA | |
| SCHEMBL17865894 | 0.89 | TP53 (0.42) | TP53KDM4EL3MBTL1LMNAGPBAR1 | |
| SCHEMBL17865884 | 0.86 | KDM4E (0.43) | TP53KDM4ENAMPTL3MBTL1LMNA | |
| SCHEMBL17865887 | 0.86 | KDM4E (0.41) | TP53KDM4EL3MBTL1LMNAGPBAR1 | |
| SCHEMBL17865896 | 0.86 | POLB (0.47) | KDM4ENPC1VNN1L3MBTL1LMNA | |
| SCHEMBL17865882 | 0.85 | LMNA (0.41) | TP53KDM4EL3MBTL1LMNAGPBAR1 | |
| SCHEMBL17865883 | 0.84 | PLAT (0.48) | KDM4ENPC1L3MBTL1LMNAGPBAR1 | |
| SCHEMBL15324681 | 0.83 | L3MBTL1 (0.39) | TP53KDM4EVNN1L3MBTL1LMNA | |
| SCHEMBL17865895 | 0.83 | KDM4E (0.39) | TP53KDM4EGPBAR1 | |
| SCHEMBL17865888 | 0.82 | KDM4E (0.42) | TP53KDM4EL3MBTL1LMNAGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836489-B1 | N-ACYL-2-(CYCLO) ALKYLPYRROLIDINES AND PIPERIDINES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2016-06-29 | — | — | EP | claimed |