SCHEMBL17865902

SCHEMBL17865902

CN(c1cc(Cl)ccc1F)C1(C)COC2(CCN(c3cnc(Cl)s3)CC2)O1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17865903 0.71 ALDH1A1 (0.31)
SCHEMBL486728 0.64 ALDH1A1 (0.42)
SCHEMBL486447 0.59 ALDH1A1 (0.30)
SCHEMBL30116237 0.56 SMN1; SMN2 (0.43)
SCHEMBL17542884 0.56 SMN1; SMN2 (0.43)
SCHEMBL29931972 0.55 ATM (0.48) FLT3
SCHEMBL17543165 0.55 ATM (0.48) FLT3
SCHEMBL23306594 0.54 ALDH1A1 (0.41)
SCHEMBL17543711 0.54 SMN1; SMN2 (0.50)
SCHEMBL17544071 0.54 SMN1; SMN2 (0.40) FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2410854-B1 SUBSTITUTED 1, 4-DIOXA-8-AZASPIRO Ý4,5¨DECANES USEFUL AS FUNGICIDES AND A PROCESS FOR THE PREPARATION THEREOF COUNCIL SCIENT IND RES (IN) 2016-06-29 EP claimed