Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | NAE1 | Q13564 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | GRK5 | P34947 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.45 |
| ▸ | NEDD8 | Q15843 | 1/20 | 0.45 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865955 | 0.84 | NAE1 (0.51) | NAE1CA2GRK5CSNK1A1UBA6 | |
| SCHEMBL192901 | 0.84 | NAE1 (0.59) | SLC29A1NAE1CA2GRK5CSNK1A1 | |
| SCHEMBL17865966 | 0.82 | SLC29A1 (0.51) | SLC29A1ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL10004854 | 0.81 | NAE1 (0.52) | NAE1CA2GRK5CSNK1A1UBA6 | |
| SCHEMBL17866058 | 0.81 | SLC29A1 (0.57) | SLC29A1ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL17865999 | 0.80 | UBA6 (0.43) | NAE1CA2GRK5CSNK1A1UBA6 | |
| SCHEMBL17865972 | 0.79 | NAE1 (0.51) | NAE1CA2GRK5CSNK1A1UBA6 | |
| SCHEMBL17865920 | 0.77 | METTL3 (0.55) | NAE1CA2GRK5CSNK1A1UBA6 | |
| SCHEMBL17865990 | 0.77 | SLC29A1 (0.57) | SLC29A1ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL17865991 | 0.76 | NAE1 (0.58) | NAE1CA2GRK5CSNK1A1UBA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402334-B1 | Inhibitors of E1 Activating Enzymes | MILLENNIUM PHARM INC (US) | 2016-06-29 | — | — | EP | claimed |