Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 5/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25167911 | 0.91 | SLC2A1 (0.41) | SLC5A1SLC5A2PTGS1PTGS2MAPK1 | |
| SCHEMBL23619235 | 0.85 | ALDH1A1 (0.43) | ALDH1A1SLC5A1SLC5A2CYP2C19CYP3A4 | |
| SCHEMBL17866069 | 0.84 | PYGB (0.42) | SLC5A1SLC5A2PTGS1PTGS2MAPK1 | |
| SCHEMBL25887782 | 0.82 | PRKD3 (0.43) | SLC5A1SLC5A2CYP3A4CYP2C9PTGS1 | |
| SCHEMBL10031320 | 0.82 | SLC5A1 (0.52) | ALDH1A1SLC5A1SLC5A2CYP2C19SOAT1 | |
| SCHEMBL2320834 | 0.81 | TLR4 (0.44) | PTGS1PTGS2SLC2A1TLR4PRKD3 | |
| SCHEMBL16259333 | 0.81 | TLR4 (0.44) | PTGS1PTGS2SLC2A1TLR4PRKD3 | |
| SCHEMBL9563973 | 0.80 | PTGS1 (0.40) | PTGS1PTGS2HSD17B10SLC2A1TLR4 | |
| SCHEMBL15963880 | 0.80 | PTGS1 (0.40) | PTGS1PTGS2HSD17B10SLC2A1TLR4 | |
| SCHEMBL6015980 | 0.80 | PTGS1 (0.40) | PTGS1PTGS2HSD17B10SLC2A1TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1782828-B1 | PROGRESSION INHIBITOR FOR DISEASE ATTRIBUTED TO ABNORMAL ACCUMULATION OF LIVER FAT | KISSEI PHARMACEUTICAL (JP) | 2016-06-29 | — | — | EP | claimed |