SCHEMBL17866890

SCHEMBL17866890

CCCCc1occ(CO)c1C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 4/20 0.38
MCL1 Q07820 4/20 0.38
KAT8 Q9H7Z6 3/20 0.38
BCL2L1 Q07817 3/20 0.38
BAK1 Q16611 3/20 0.38
PPARA Q07869 3/20 0.38
PPARG P37231 2/20 0.38
EP300 Q09472 2/20 0.38
KAT5 Q92993 2/20 0.38
KAT2A Q92830 1/20 0.38
KAT2B Q92831 1/20 0.38
SAE1 Q9UBE0 1/20 0.38
GABRP O00591 2/20 0.37
GABRD O14764 2/20 0.37
GABRA1 P14867 2/20 0.37
GABRB1 P18505 2/20 0.37
GABRG2 P18507 2/20 0.37
GABRB3 P28472 2/20 0.37
GABRA5 P31644 2/20 0.37
GABRA3 P34903 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17867211 0.95 KAT8 (0.43) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL16433085 0.90 PTPN1 (0.40) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL27816116 0.84 BID (0.51) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL16432984 0.79 ACE2 (0.31) ALDH1A1METAP2
SCHEMBL20550358 0.75 ALDH1A1 (0.41) RARBALDH1A1HPGD
SCHEMBL17867056 0.75 MAPT (0.32) ALDH1A1
SCHEMBL12477522 0.73 BID (0.43) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL16432884 0.73 MAOB (0.31)
SCHEMBL27811264 0.73 BID (0.43) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL9957129 0.73 POLB (0.39) BIDMCL1KAT8BCL2L1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed