SCHEMBL17867211

SCHEMBL17867211

CCCCCc1occ(CO)c1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 5/20 0.43
PPARA Q07869 4/20 0.43
BID P55957 3/20 0.43
MCL1 Q07820 3/20 0.43
BCL2L1 Q07817 2/20 0.43
BAK1 Q16611 2/20 0.43
PPARG P37231 2/20 0.43
EP300 Q09472 2/20 0.43
KAT5 Q92993 2/20 0.43
SAE1 Q9UBE0 2/20 0.43
KAT2A Q92830 1/20 0.43
KAT2B Q92831 1/20 0.43
F7 P08709 3/20 0.38
F3 P13726 3/20 0.38
MMP2 P08253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.38
ECE1 P42892 1/20 0.38
SGMS1 Q86VZ5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17866890 0.95 BID (0.38) KAT8PPARABIDMCL1BCL2L1
SCHEMBL27816116 0.89 BID (0.51) KAT8PPARABIDMCL1BCL2L1
SCHEMBL16433085 0.89 PTPN1 (0.40) KAT8PPARABIDMCL1BCL2L1
SCHEMBL16432984 0.78 ACE2 (0.31)
SCHEMBL29173227 0.75 BID (0.41) KAT8PPARABIDMCL1BCL2L1
SCHEMBL28994451 0.74 BID (0.49) KAT8PPARABIDMCL1BCL2L1
SCHEMBL20550358 0.74 ALDH1A1 (0.41) MAPTRARB
SCHEMBL17867056 0.74 MAPT (0.32) MAPT
SCHEMBL28993973 0.73 BID (0.51) KAT8PPARABIDMCL1BCL2L1
SCHEMBL16432884 0.72 MAOB (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed