SCHEMBL17866922

SCHEMBL17866922

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)CCCNC(=N)N

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 18/20 0.45
NPY1R P25929 11/20 0.45
NPY5R Q15761 10/20 0.45
NPY2R P49146 7/20 0.45
CTSK P43235 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17866918 1.00 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2RCTSK
SCHEMBL17867003 0.90 NPY4R (0.47) NPY4RNPY1RNPY5RNPY2RCTSK
SCHEMBL17867009 0.90 NPY4R (0.47) NPY4RNPY1RNPY5RNPY2RCTSK
SCHEMBL13724544 0.87 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2R
SCHEMBL1818349 0.87 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2R
SCHEMBL17867227 0.86 ENPEP (0.35) CTSK
SCHEMBL6674182 0.86 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2R
SCHEMBL17867224 0.86 ENPEP (0.35) CTSK
Leupeptin SCHEMBL13933715 0.86 NPY4R (0.46) NPY4RNPY1RNPY5RNPY2R
Leupeptin SCHEMBL11021602 0.86 NPY4R (0.46) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed