SCHEMBL17866955

SCHEMBL17866955

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nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.35
MPI P34949 1/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14659599 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL20281001 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL6473099 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL3276506 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL16431695 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL9985445 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL3281934 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL2338047 0.93 AKR1B1 (0.36) AKR1B1MPITHRB
SCHEMBL448041 0.93 AKR1B1 (0.36) AKR1B1MPITHRB
SCHEMBL7153437 0.93 AKR1B1 (0.36) AKR1B1MPITHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed