SCHEMBL6473099

SCHEMBL6473099

O=CC(O)C(O)C(O)C(O)CCO

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.35
MPI P34949 1/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14659599 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL20281001 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL3276506 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL16431695 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL17866955 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL9985445 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL3281934 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL2338047 0.93 AKR1B1 (0.36) AKR1B1MPITHRB
SCHEMBL448041 0.93 AKR1B1 (0.36) AKR1B1MPITHRB
SCHEMBL7153437 0.93 AKR1B1 (0.36) AKR1B1MPITHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250127925-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2025-04-24 US disclosed
US-12076418-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo ENGENE, INC. (CA) 2024-09-03 US disclosed
CN-117843739-A Campylobacter jejuni surface trisaccharide conjugate and preparation method and application thereof 江苏食品药品职业技术学院 2024-04-09 CN disclosed
US-20220133907-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2022-05-05 US disclosed
EP-3970697-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO Engene, Inc. (CA) 2022-03-23 EP disclosed
US-11167045-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo HERCULES CAPITAL, INC. 2021-11-09 US disclosed
EP-3049473-B1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO ENGENE INC (CA) 2021-09-22 EP disclosed
US-10765627-B2 Immunogenic composition against Campylobacter jejuni THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2020-09-08 US disclosed
US-20200061208-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2020-02-27 US disclosed
US-20190336440-A1 Immunogenic Composition Against Campylobacter Jejuni UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2019-11-07 US disclosed
US-9308246-B2 Capsule composition for use as immunogen against Campylobacter jejuni THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2016-04-12 US disclosed
WO-2016022412-A1 IMMUNOGENIC COMPOSITION AGAINST CAMPYLOBACTER JEJUNI THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2016-02-11 WO disclosed
US-20150273037-A1 Immunogenic composition against Campylobacter jejuni UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2015-10-01 US disclosed
US-20150031863-A1 CONJUGATING AMINES THE GENERAL HOSPITAL CORPORATION (US) 2015-01-29 US disclosed
WO-2013009826-A9 CONJUGATING AMINES THE GENERAL HOSPITAL CORPORATION (US) 2013-03-21 WO disclosed
WO-2013009826-A1 CONJUGATING AMINES THE GENERAL HOSPITAL CORPORATION (US) 2013-01-17 WO disclosed
WO-2012166587-A1 CAPSULE COMPOSITION FOR USE AS IMMUNOGEN AGAINST CAMPYLOBACTER JEJUNI THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2012-12-06 WO disclosed
US-20110300173-A1 Capsule composition for use as immunogen against Campylobacter jejuni UNITED STATES GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE NAVY 2011-12-08 US disclosed
WO-2005017129-A1 PHOSPHORAMIDE AND USES THEREOF NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2005-02-24 WO disclosed
US-5157116-A Antidiabetic agents MERRELL DOW PHARMACEUTICALS INC. (US) 1992-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110300173-A1 Capsule composition for use as immunogen against Campylobacter jejuni CAPG, ST3GAL3, ICOS AKR1B1 4337/4885MPI 630/4885LMNA 4219/4885
US-20200061208-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP AKR1B1 3046/4885MPI 2113/4885LMNA 1219/4885
US-20250127925-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP AKR1B1 3046/4885MPI 2113/4885LMNA 1219/4885
US-10765627-B2 Immunogenic composition against Campylobacter jejuni TLR6, TLR2, SIGLEC9 AKR1B1 3981/4885MPI 208/4885LMNA 3469/4885
US-20190336440-A1 Immunogenic Composition Against Campylobacter Jejuni TLR6, TLR2, SIGLEC9 AKR1B1 3981/4885MPI 208/4885LMNA 3469/4885
US-20150031863-A1 CONJUGATING AMINES CD47, CD58, CD44 AKR1B1 3571/4885MPI 2736/4885LMNA 2936/4885
US-11167045-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo CSGALNACT1, CHI3L2, LNPEP AKR1B1 3046/4885MPI 2113/4885LMNA 1219/4885
US-12076418-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo CSGALNACT1, CHI3L2, LNPEP AKR1B1 3046/4885MPI 2113/4885LMNA 1219/4885
US-20150273037-A1 Immunogenic composition against Campylobacter jejuni TLR6, TLR2, TLR9 AKR1B1 3982/4885MPI 221/4885LMNA 3446/4885
US-20220133907-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP AKR1B1 3046/4885MPI 2113/4885LMNA 1219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.