SCHEMBL3276506

SCHEMBL3276506

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nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.35
MPI P34949 1/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14659599 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL20281001 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL6473099 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL16431695 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL17866955 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL9985445 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL3281934 1.00 AKR1B1 (0.35) AKR1B1MPILMNAL3MBTL1TDP1
SCHEMBL2338047 0.93 AKR1B1 (0.36) AKR1B1MPITHRB
SCHEMBL448041 0.93 AKR1B1 (0.36) AKR1B1MPITHRB
SCHEMBL7153437 0.93 AKR1B1 (0.36) AKR1B1MPITHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4183408-A1 COMBINED ENTEROTOXIGENIC ESCHERICHIA COLI AND SHIGELLA RECOMBINANT The United States of America as Represented by The Secretary of the Navy (US) 2023-05-24 EP claimed
EP-3197485-B1 COMBINED ENTEROTOXIGENIC ESCHERICHIA COLI AND CAMPYLOBACTER JEJUNI RECOMBINANT CONSTRUCT US NAVY (US) 2022-11-02 EP claimed
US-11077200-B2 Combined enteropathogen recombinant construct THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2021-08-03 US claimed
US-20190008979-A1 Combined enteropathogen recombinant construct UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2019-01-10 US claimed
US-10105448-B2 Combined enteropathogen recombinant construct THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2018-10-23 US claimed
US-20170266300-A9 Combined enteropathogen recombinant construct UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2017-09-21 US claimed
EP-3197485-A1 COMBINED ENTEROTOXIGENIC ESCHERICHIA COLI AND CAMPYLOBACTER JEJUNI RECOMBINANT CONSTRUCT The United States of America as Represented by The Secretary of the Navy (US) 2017-08-02 EP claimed
EP-3188748-A1 IMMUNOGENIC COMPOSITION AGAINST CAMPYLOBACTER JEJUNI The United States of America as Represented by The Secretary of the Navy (US) 2017-07-12 EP claimed
WO-2016022412-A9 IMMUNOGENIC COMPOSITION AGAINST CAMPYLOBACTER JEJUNI THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2016-05-12 WO claimed
WO-2016048810-A1 COMBINED ENTEROTOXIGENIC ESCHERICHIA COLI AND CAMPYLOBACTER JEJUNI RECOMBINANT CONSTRUCT THE UNITED STATES OF AMERICA AS REPRESENTED BY TH SECRETARY OF THE NAVY (US) 2016-03-31 WO claimed
WO-2016022412-A1 IMMUNOGENIC COMPOSITION AGAINST CAMPYLOBACTER JEJUNI THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2016-02-11 WO claimed
US-20150273037-A1 Immunogenic composition against Campylobacter jejuni UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2015-10-01 US claimed
US-20150258201-A1 Combined enteropathogen recombinant construct GUERRY PATRICIA (US) 2015-09-17 US claimed
EP-2786763-A1 Capsule composition for use as immunogen against Campylobacter jejuni The United States of America as Represented by The Secretary of the Navy (US) 2014-10-08 EP claimed
US-7700578-B2 Capsule composition for use as immunogen against Campylobacter jejuni THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2010-04-20 US claimed
US-20090004223-A1 Capsule composition for use as immunogen against campylobacter jejuni UNITED STATES OF AMERICA AS REPRESENTED BY THE SEC. OF THE NAVY 2009-01-01 US claimed
CN-118420796-A Synthesis method and application of campylobacter jejuni CG8486 capsular oligosaccharide and glycoprotein conjugate thereof 中国海洋大学 2024-08-02 CN disclosed
CN-118420796-A Synthesis method and application of campylobacter jejuni CG8486 capsular oligosaccharide and glycoprotein conjugate thereof 中国海洋大学 2024-08-02 CN disclosed
WO-2009017666-A1 CAPSULE COMPOSITION FOR USE AS IMMUNOGEN AGAINST CAMPYLOBACTER JEJUNI THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2009-02-05 WO disclosed
US-20090004223-A1 Capsule composition for use as immunogen against campylobacter jejuni UNITED STATES OF AMERICA AS REPRESENTED BY THE SEC. OF THE NAVY 2009-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10105448-B2 Combined enteropathogen recombinant construct NOD2, TLR6, TLR2 AKR1B1 1830/4885MPI 605/4885LMNA 4277/4885
US-20090004223-A1 Capsule composition for use as immunogen against campylobacter jejuni ST3GAL3, DDOST, CAPG AKR1B1 4451/4885MPI 291/4885LMNA 4534/4885
US-20150258201-A1 Combined enteropathogen recombinant construct NOD2, TLR6, TLR2 AKR1B1 1830/4885MPI 605/4885LMNA 4277/4885
US-11077200-B2 Combined enteropathogen recombinant construct NOD2, TLR6, TLR2 AKR1B1 1830/4885MPI 605/4885LMNA 4277/4885
US-20170266300-A9 Combined enteropathogen recombinant construct NOD2, TLR6, TLR2 AKR1B1 1830/4885MPI 605/4885LMNA 4277/4885
US-20150273037-A1 Immunogenic composition against Campylobacter jejuni TLR6, TLR2, TLR9 AKR1B1 3982/4885MPI 221/4885LMNA 3446/4885
US-20190008979-A1 Combined enteropathogen recombinant construct NOD2, TLR6, TLR2 AKR1B1 1830/4885MPI 605/4885LMNA 4277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.