SCHEMBL17867007

SCHEMBL17867007

CC1(O)c2cccc(O)c2C(=O)CC1CO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
STAT3 P40763 1/20 0.40
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
AKR1C3 P42330 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
TXNRD1 Q16881 1/20 0.34
TXNRD3 Q86VQ6 1/20 0.34
TXNRD2 Q9NNW7 1/20 0.34
MEN1 O00255 6/20 0.34
KMT2A Q03164 6/20 0.34
KDM4E B2RXH2 3/20 0.34
TDP1 Q9NUW8 3/20 0.34
MAPT P10636 3/20 0.34
USP2 O75604 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11242496 0.68 TXNRD1 (0.41) STAT3MAOAMAOBCA1CA2
SCHEMBL27661112 0.62 STAT3 (0.48) STAT3MAOAMAOBMEN1KMT2A
SCHEMBL9142162 0.62 GRK6 (0.42) MAOAMAOBCA1CA2CA7
SCHEMBL28137965 0.61 STAT3 (0.54) STAT3MAOAMAOBCA1CA2
SCHEMBL18971575 0.60 CA1 (0.37) MMP2STAT3MAOAMAOBCA1
SCHEMBL3163061 0.60 TXNRD1 (0.41) MAOAMAOBCA1CA2CA7
SCHEMBL18971656 0.59 CA1 (0.46) STAT3MAOAMAOBCA1CA2
SCHEMBL28813644 0.59 MAOA (0.59) STAT3MAOAMAOBAKR1C3MEN1
Isoshinanolone SCHEMBL18971653 0.59 STAT3 (0.44) STAT3MAOAMAOBMEN1KMT2A
Isoshinanolone SCHEMBL27602355 0.59 STAT3 (0.44) STAT3MAOAMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed