Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.35 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.34 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.34 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.34 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.34 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.34 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.34 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.34 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.34 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.34 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.34 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.34 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.34 |
| ▸ | PSMA8 | Q8TAA3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30819201 | 1.00 | KDM4E (0.38) | KDM4ESOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL29375137 | 1.00 | KDM4E (0.38) | KDM4ESOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL29885671 | 0.95 | PSMB11 (0.38) | KDM4EPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL29885414 | 0.92 | SOAT2 (0.41) | SOAT1GHSRSOAT2 | |
| SCHEMBL16500668 | 0.84 | KDM4E (0.47) | KDM4ESOAT1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6466586 | 0.84 | KDM4E (0.47) | KDM4ESOAT1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL29717170 | 0.84 | KDM4E (0.47) | KDM4ESOAT1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL29375200 | 0.84 | PSMB11 (0.46) | SOAT1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL13637393 | 0.84 | KDM4E (0.39) | KDM4ESOAT1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL2869111 | 0.83 | HRH3 (0.39) | ALDH1A1MLNRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |