SCHEMBL17867200

SCHEMBL17867200

CCC(C)c1ncc(CC(C)C)nc1OC

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 2/20 0.35
CD274 Q9NZQ7 2/20 0.35
MAP4K1 Q92918 4/20 0.31
PDE10A Q9Y233 1/20 0.30
TRPM8 Q7Z2W7 1/20 0.30
P2RX3 P56373 1/20 0.30
P2RX2 Q9UBL9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31442983 1.00 PDCD1 (0.35) PDCD1CD274MAP4K1PDE10ATRPM8
SCHEMBL31560062 1.00 PDCD1 (0.35) PDCD1CD274MAP4K1PDE10ATRPM8
SCHEMBL31442984 1.00 PDCD1 (0.35) PDCD1CD274MAP4K1PDE10ATRPM8
SCHEMBL31442986 0.88 PDCD1 (0.32) PDCD1CD274
SCHEMBL16431612 0.85 PDCD1 (0.35) PDCD1CD274PDE10ATRPM8P2RX3
SCHEMBL30505752 0.80 TRPM8 (0.37) PDE10ATRPM8P2RX3P2RX2
SCHEMBL29131679 0.80 TRPM8 (0.37) PDE10ATRPM8P2RX3P2RX2
SCHEMBL16432838 0.77 NOS3 (0.36) PDE10ATRPM8P2RX3P2RX2
SCHEMBL31442991 0.77 TRPM8 (0.38) PDCD1CD274PDE10ATRPM8P2RX3
SCHEMBL31442989 0.77 TRPM8 (0.38) PDCD1CD274PDE10ATRPM8P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025088253-A1 PYRAZINE DERIVATIVES AS BIOCONTROL AND SPRINGTAIL ATTRACTANT AGENTS FOR CONTROLLING FUNGAL DISEASES IN CEREALS MUSÉUM NATIONAL D'HISTOIRE NATURELLE (FR) 2025-05-01 WO disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed