SCHEMBL17867238

SCHEMBL17867238

CCC(C)c1cnc(C(C)C)c(OC)n1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 2/20 0.37
CD274 Q9NZQ7 2/20 0.37
MAP4K1 Q92918 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6124109 0.84 PDCD1 (0.38) PDCD1CD274
SCHEMBL16431745 0.81 CRHR1 (0.31)
SCHEMBL8585099 0.73 PDCD1 (0.38) PDCD1CD274
SCHEMBL2554173 0.73 PDCD1 (0.38) PDCD1CD274
SCHEMBL12726916 0.73 PDCD1 (0.41) PDCD1CD274
SCHEMBL16431612 0.71 PDCD1 (0.35) PDCD1CD274
SCHEMBL31442983 0.71 PDCD1 (0.35) PDCD1CD274MAP4K1
SCHEMBL31560062 0.71 PDCD1 (0.35) PDCD1CD274MAP4K1
SCHEMBL17867200 0.71 PDCD1 (0.35) PDCD1CD274MAP4K1
SCHEMBL31442984 0.71 PDCD1 (0.35) PDCD1CD274MAP4K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed