Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4873099 | 0.95 | TSHR (0.46) | TSHR | |
| SCHEMBL4438485 | 0.95 | — | — | |
| SCHEMBL18918455 | 0.95 | — | — | |
| SCHEMBL10713958 | 0.95 | TSHR (0.46) | TSHR | |
| SCHEMBL22489 | 0.95 | — | — | |
| SCHEMBL1789456 | 0.91 | — | — | |
| Cyclohexane SCHEMBL7515073 | 0.91 | TSHR (0.42) | TSHR | |
| SCHEMBL28908204 | 0.91 | — | — | |
| Water SCHEMBL28636710 | 0.91 | — | — | |
| Methane SCHEMBL29241723 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592611-B2 | Trioxane dimer sulfur compounds | THE JOHNS HOPKINS UNIVERSITY (US) | 2013-11-26 | — | — | US | disclosed |
| EP-2328579-B1 | TRIOXANE DIMER SULFUR COMPOUNDS | UNIV JOHNS HOPKINS (US) | 2013-10-23 | — | — | EP | disclosed |
| EP-2328579-A1 | TRIOXANE DIMER SULFUR COMPOUNDS | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-06-08 | — | — | EP | disclosed |
| US-20110124603-A1 | Trioxane Dimer Sulfur Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-05-26 | — | — | US | disclosed |
| WO-2010009428-A1 | TRIOXANE DIMER SULFUR COMPOUNDS | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124603-A1 | Trioxane Dimer Sulfur Compounds | HCCS, SQOR, SFXN1 | TSHR 2984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.