SCHEMBL17867302

SCHEMBL17867302

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nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 1/20 0.44
▸ ENPEP Q07075 11/20 0.43
▸ FNTA P49354 4/20 0.43
▸ FNTB P49356 4/20 0.43
▸ MME P08473 1/20 0.41
▸ ACE P12821 1/20 0.41
▸ CPA1 P15085 1/20 0.41
▸ ACE2 Q9BYF1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17867299 1.00 BACE1 (0.44) BACE1ENPEPFNTAFNTBMME
SCHEMBL30051524 0.94 MME (0.46) ENPEPFNTAFNTBMMEACE
SCHEMBL30736286 0.92 BACE1 (0.49) BACE1ENPEPFNTAFNTB
SCHEMBL30051366 0.90 ENPEP (0.49) ENPEPFNTAFNTB
SCHEMBL30051929 0.90 ENPEP (0.44) ENPEPFNTAFNTB
SCHEMBL29349967 0.89 LMNA (0.45) BACE1FNTAFNTB
SCHEMBL30011954 0.86 LMNA (0.43) BACE1FNTAFNTB
SCHEMBL30051191 0.86 ENPEP (0.47) ENPEP
SCHEMBL29931588 0.85 ENPEP (0.53) BACE1ENPEPFNTAFNTB
SCHEMBL31432463 0.85 FOLH1 (0.48) ENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 — — US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 — — US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 — — US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 — — US disclosed
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