SCHEMBL17867434

SCHEMBL17867434

CC1C(=O)c2c(O)cc(O)cc2OC1c1ccc(O)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CBS P35520 1/20 0.67
ESR1 P03372 4/20 0.63
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
POLB P06746 2/20 0.62
MAPT P10636 2/20 0.62
THRB P10828 1/20 0.62
HTT P42858 1/20 0.62
BLM P54132 1/20 0.62
ESR2 Q92731 3/20 0.59
CYP3A4 P08684 4/20 0.59
RECQL P46063 2/20 0.59
CYP1A2 P05177 2/20 0.59
ALOX12 P18054 2/20 0.59
HSD17B10 Q99714 2/20 0.59
SOST Q9BQB4 2/20 0.59
KDM4E B2RXH2 1/20 0.59
GAA P10253 1/20 0.59
ALOX15 P16050 1/20 0.59
NFKB1 P19838 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13017768 0.89 RECQL (0.76) CBSESR1MEN1KMT2APOLB
Chamaejasmin SCHEMBL29479818 0.87 CBS (0.81) CBSESR1MEN1KMT2APOLB
Chamaejasmin SCHEMBL27478340 0.87 CBS (0.81) CBSESR1MEN1KMT2APOLB
Chamaejasmin SCHEMBL6354453 0.87 CBS (0.81) CBSESR1MEN1KMT2APOLB
Chamaejasmin SCHEMBL29369743 0.87 CBS (0.81) CBSESR1MEN1KMT2APOLB
Dihydrokaempferol SCHEMBL39319 0.85 CYP3A4 (0.80) CBSESR1MEN1KMT2APOLB
Dihydrokaempferol SCHEMBL3438673 0.85 CYP3A4 (0.80) CBSESR1MEN1KMT2APOLB
Dihydrokaempferol SCHEMBL31026899 0.85 CYP3A4 (0.80) CBSESR1MEN1KMT2APOLB
Dihydrokaempferol SCHEMBL29367287 0.85 CYP3A4 (0.80) CBSESR1MEN1KMT2APOLB
Dihydrokaempferol SCHEMBL13354175 0.85 CYP3A4 (0.80) CBSESR1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed