Dihydrokaempferol

Dihydrokaempferol

SCHEMBL39319

O=C1c2c(O)cc(O)cc2OC(c2ccc(O)cc2)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.80
MEN1 O00255 4/20 0.80
KMT2A Q03164 4/20 0.80
MAPT P10636 4/20 0.80
HSD17B10 Q99714 4/20 0.80
ALOX15 P16050 4/20 0.80
ALOX12 P18054 3/20 0.80
RECQL P46063 2/20 0.80
SOST Q9BQB4 2/20 0.80
POLB P06746 2/20 0.80
CYP1A2 P05177 2/20 0.80
KDM4E B2RXH2 2/20 0.80
GAA P10253 2/20 0.80
HIF1A Q16665 2/20 0.80
NFKB1 P19838 1/20 0.80
MAPK1 P28482 1/20 0.80
SYNJ2 O15056 1/20 0.74
APP P05067 1/20 0.74
XDH P47989 1/20 0.66
CBS P35520 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dihydrokaempferol SCHEMBL31026899 1.00 CYP3A4 (0.80) CYP3A4MEN1KMT2AMAPTHSD17B10
Dihydrokaempferol SCHEMBL2036629 1.00 CYP3A4 (0.80) CYP3A4MEN1KMT2AMAPTHSD17B10
Dihydrokaempferol SCHEMBL3437565 1.00 CYP3A4 (0.80) CYP3A4MEN1KMT2AMAPTHSD17B10
Dihydrokaempferol SCHEMBL29454736 1.00 CYP3A4 (0.80) CYP3A4MEN1KMT2AMAPTHSD17B10
Dihydrokaempferol SCHEMBL13354175 1.00 CYP3A4 (0.80) CYP3A4MEN1KMT2AMAPTHSD17B10
Dihydrokaempferol SCHEMBL29367287 1.00 CYP3A4 (0.80) CYP3A4MEN1KMT2AMAPTHSD17B10
Dihydrokaempferol SCHEMBL3438673 1.00 CYP3A4 (0.80) CYP3A4MEN1KMT2AMAPTHSD17B10
Dihydrokaempferol SCHEMBL31547241 0.93 MAPT (0.70) CYP3A4MEN1KMT2AMAPTHSD17B10
Pinobaksin SCHEMBL14461145 0.91 MAPT (0.75) CYP3A4MEN1KMT2AMAPTHSD17B10
Pinobaksin SCHEMBL1045054 0.91 MAPT (0.75) CYP3A4MEN1KMT2AMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2272 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122038322-A 4-Hydroxyphenylacetic acid 3-monooxygenase mutant and application thereof 南京林业大学 2026-05-15 CN claimed
EP-3346842-B1 STABLE INOCULANT COMPOSITIONS AND METHODS FOR PRODUCING SAME NOVONESIS PLANT BIOSOLUTIONS AS (DK) 2026-03-25 EP claimed
US-12514929-B2 Deformable nano-scale vehicles (DNVS) for trans-blood brain barrier, trans-mucosal, and transdermal drug delivery THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-06 US claimed
US-12454714-B2 Monbretin A (MbA) synthesis using a heterologous nucleic acid(s) encoding A MbA pathway enzyme THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2025-10-28 US claimed
EP-4218783-B1 FRUIT EXTRACTS PROVEXIS NATURAL PRODUCTS LTD (GB) 2025-07-30 EP claimed
US-20250212873-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-03 US claimed
EP-4573202-A2 FLAVONOID BIOPRODUCTION USING MICROORGANISM HOSTS Debut Biotechnology, Inc. (US) 2025-06-25 EP claimed
CN-120053346-A Lotus seedpod or lotus seed shell extract and preparation method and application thereof 湖南科技大学 2025-05-30 CN claimed
CN-120019153-A Biological production of flavonoids using microbial hosts 德比生物技术公司 2025-05-16 CN claimed
CN-118813576-B Protein coded by safflower CtHA gene and application thereof 新疆农业科学院经济作物研究所(新疆维吾尔自治区棉花研究所新疆维吾尔自治区甜菜改良中心) 2025-04-04 CN claimed
EP-1072265-A1 Use of plant polyphenols for treating iron overload MEDIS S.r.l. Medical Infusion Systems (IT) 2001-01-31 EP claimed
US-5948955-A Transgenic plants having altered anthocyann levels INTERNATIONAL FLOWER DEVELOPMENTS PTY LTD (AU) 1999-09-07 US claimed
US-5861487-A HYDROXYLASE ENZYME CAPABLE OF HYDROXYLATING DIHYDROKEMPFEROL, CULTURES OF CELLS AND RECOVERING HYDROLYLASE INTERNATIONAL FLOWER DEVELOPMENTS PTY. LTD. (AU) 1999-01-19 US claimed
US-5639870-A DNA FOR TRANSGENIC PIGMENTING INTERNATIONAL FLOWER DEVELOPMENTS PTY., LTD. (AU) 1997-06-17 US claimed
US-5410096-A Plants with modified flower color and methods for their production by genetic engineering MEYER PETER (DE) 1995-04-25 US claimed
US-5349125-A Flower pigmentation INTERNATIONAL FLOWER DEVELOPMENTS PTY. LTD. (AU) 1994-09-20 US claimed
EP-0316797-B1 Plants with a modified flowering colour and genetic engineering method for their production MAX PLANCK GESELLSCHAFT (DE) 1993-10-20 EP claimed
WO-1993001290-A1 GENETIC SEQUENCES ENCODING FLAVONOID PATHWAY ENZYMES AND USES THEREFOR INTERNATIONAL FLOWER DEVELOPMENTS PTY. LTD. (AU) 1993-01-21 WO claimed
EP-0522880-A2 Genetic sequences encoding flavonoid pathway enzymes and uses therefor INTERNATIONAL FLOWER DEVELOPMENTS Pty. Ltd. (AU) 1993-01-13 EP claimed
EP-0316797-A2 Plants with a modified flowering colour and genetic engineering method for their production Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1989-05-24 EP claimed