SCHEMBL1786749

SCHEMBL1786749

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nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FGF1 P05230 5/20 0.48
FGF2 P09038 2/20 0.48
SERPINC1 P01008 1/20 0.39
HPSE Q9Y251 11/20 0.36
F10 P00742 1/20 0.33
BDNF P23560 2/20 0.31
PTN P21246 1/20 0.31
MDK P21741 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1789358 1.00 FGF1 (0.48) FGF1FGF2SERPINC1HPSEF10
SCHEMBL12798095 1.00 FGF1 (0.48) FGF1FGF2SERPINC1HPSEF10
SCHEMBL16329943 1.00 FGF1 (0.48) FGF1FGF2SERPINC1HPSEF10
SCHEMBL14368581 1.00 FGF1 (0.48) FGF1FGF2SERPINC1HPSEF10
SCHEMBL1786656 1.00 FGF1 (0.48) FGF1FGF2SERPINC1HPSEF10
SCHEMBL14368576 1.00 FGF1 (0.48) FGF1FGF2SERPINC1HPSEF10
SCHEMBL14368288 1.00 FGF1 (0.48) FGF1FGF2SERPINC1HPSEF10
SCHEMBL1786663 0.96 FGF1 (0.45) FGF1FGF2SERPINC1HPSEBDNF
SCHEMBL12798102 0.96 FGF1 (0.45) FGF1FGF2SERPINC1HPSEBDNF
SCHEMBL16317603 0.93 FGF1 (0.50) FGF1FGF2SERPINC1HPSEBDNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987216-B2 Polysulfated glycosides and salts thereof Teva Hungary Pharmaceutical Marketing Private Limited Company (HU) 2015-03-24 US claimed
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RESEARCH INSTITUTE LTD. (HU) 2011-05-19 US claimed
US-7902158-B2 Polysulfated glycosides and salts thereof Ivax Drug Research Ltd. (HU) 2011-03-08 US claimed
EP-1778709-B1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RES INST LTD (HU) 2008-05-28 EP claimed
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2007-12-06 US claimed
EP-1778709-A2 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX Drug Research Institute Ltd (HU) 2007-05-02 EP claimed
WO-2006017726-A2 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2006-02-16 WO claimed
US-8987216-B2 Polysulfated glycosides and salts thereof Teva Hungary Pharmaceutical Marketing Private Limited Company (HU) 2015-03-24 US disclosed
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RESEARCH INSTITUTE LTD. (HU) 2011-05-19 US disclosed
US-7902158-B2 Polysulfated glycosides and salts thereof Ivax Drug Research Ltd. (HU) 2011-03-08 US disclosed
EP-1778709-B1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RES INST LTD (HU) 2008-05-28 EP disclosed
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2007-12-06 US disclosed
EP-1778709-A2 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX Drug Research Institute Ltd (HU) 2007-05-02 EP disclosed
WO-2006017726-A2 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2006-02-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF CFTR, AREG, STS FGF1 1447/4885FGF2 919/4885SERPINC1 222/4885
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof CFTR, AREG, STS FGF1 1447/4885FGF2 919/4885SERPINC1 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.