Apaflurane

Apaflurane

SCHEMBL17867718

C.FC(C(F)(F)F)C(F)(F)F

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Apaflurane SCHEMBL19860 0.95 ALDH1A1 (0.33) ALDH1A1HSD17B10MEN1KMT2A
Apaflurane SCHEMBL7649343 0.90 ALDH1A1 (0.31) ALDH1A1HSD17B10MEN1KMT2A
Apaflurane SCHEMBL27772978 0.90 ALDH1A1 (0.31) ALDH1A1HSD17B10MEN1KMT2A
Apaflurane SCHEMBL7649339 0.86
Apaflurane SCHEMBL5545395 0.86
Apaflurane SCHEMBL9159453 0.79
Perflutren SCHEMBL9417226 0.79 LMNA (0.30)
Apaflurane SCHEMBL28066334 0.79 MEN1 (0.32) MEN1KMT2A
SCHEMBL17158623 0.76
SCHEMBL1274333 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10308867-B2 Fluid composition and method for stimulation in the field of oil and gas production ARKEMA FRANCE (FR) 2019-06-04 US disclosed
US-10253247-B2 Fluid composition and method for stimulation in the field of oil and gas production ARKEMA FRANCE (FR) 2019-04-09 US disclosed
US-20160186047-A1 FLUID COMPOSITION FOR STIMULATION IN THE FIELD OF OIL AND GAS PRODUCTION ARKEMA FRANCE (FR) 2016-06-30 US disclosed
US-20160186046-A1 FLUID COMPOSITION FOR STIMULATION IN THE FIELD OF OIL AND GAS PRODUCTION ARKEMA FRANCE (FR) 2016-06-30 US disclosed