Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737881 | 0.85 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL1784622 | 0.85 | TSHR (0.52) | ALDH1A1TSHRFAAHTRPV1TDP1 | |
| SCHEMBL1784663 | 0.85 | TSHR (0.52) | ALDH1A1TSHRFAAHTRPV1TDP1 | |
| SCHEMBL1783265 | 0.83 | TSHR (0.52) | ALDH1A1TSHRFAAHTRPV1HIF1A | |
| SCHEMBL1787521 | 0.83 | TSHR (0.52) | ALDH1A1TSHRFAAHTRPV1TDP1 | |
| SCHEMBL1782658 | 0.81 | — | — | |
| SCHEMBL10977912 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TSHRFAAHTRPV1TDP1 | |
| SCHEMBL27495248 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TSHRHIF1A | |
| SCHEMBL1786336 | 0.77 | TRPA1 (0.42) | ALDH1A1TSHR | |
| SCHEMBL1786334 | 0.77 | TRPA1 (0.42) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102272078-B | Method for producing polymethylols | BASF SE | 2015-06-03 | — | — | CN | disclosed |
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| CN-102272078-A | Method for producing polymethylols | — | 2011-12-07 | — | — | CN | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| US-7186782-B2 | Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer | TSRC CORPORATION (TW) | 2007-03-06 | — | — | US | disclosed |
| US-20060041079-A1 | Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer | TSRC CORPORATION | 2006-02-23 | — | — | US | disclosed |
| CN-1674884-A | Synergistic combination of an alpha-2-delta ligand and a PDEV inhibitor for use in the treatment of pain | PFIZER LTD (US) | 2005-09-28 | — | — | CN | disclosed |
| US-6881797-B2 | Process for hydrogenation of conjugated diene polymer | TSRC CORPORATION (TW) | 2005-04-19 | — | — | US | disclosed |
| US-20040082727-A1 | Process for hydrogenation of conjugated diene polymer | TSRC CORPORATION (CN) | 2004-04-29 | — | — | US | disclosed |
| US-5998635-A | CATALYTIC CYCLIZATION AN ALDEHYDE WITH A KETENE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0912490-A1 | ESTERS, ETHERS, AND COMPOSITIONS COMPRISING THEM | EXXON CHEMICAL PATENTS INC. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003462-A1 | ESTERS, ETHERS, AND COMPOSITIONS COMPRISING THEM | EXXON CHEMICAL PATENTS, INC. (US) | 1998-01-29 | — | — | WO | disclosed |
| WO-1998002406-A1 | RECYCLE AND RECOVERY OF USEFUL PRODUCTS FROM HEAVY ALDOL BY-PRODUCTS | EXXON CHEMICAL PATENTS, INC. (US) | 1998-01-22 | — | — | WO | disclosed |
| EP-0804402-A1 | ORGANIC COMPOUNDS AND PROCESSES FOR THEIR MANUFACTURE | EXXON CHEMICAL PATENTS INC. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996022268-A1 | ORGANIC COMPOUNDS AND PROCESSES FOR THEIR MANUFACTURE | EXXON CHEMICAL PATENTS INC. (US) | 1996-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | ALDH1A1 520/4885TSHR 2479/4885FAAH 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.