Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.33 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.33 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25971336 | 1.00 | APLNR (0.46) | APLNREPHX2GRM2GRM3GRM4 | |
| SCHEMBL17414390 | 1.00 | APLNR (0.46) | APLNREPHX2GRM2GRM3GRM4 | |
| SCHEMBL715584 | 0.86 | APLNR (0.43) | APLNRCYP1A2GABRPGABRDGABRA1 | |
| SCHEMBL23457777 | 0.86 | APLNR (0.43) | APLNRCYP1A2GABRPGABRDGABRA1 | |
| SCHEMBL30879578 | 0.86 | APLNR (0.43) | APLNRCYP1A2GABRPGABRDGABRA1 | |
| SCHEMBL1840371 | 0.85 | EPHX2 (0.40) | APLNREPHX2GRM2GRM3GRM4 | |
| SCHEMBL18569711 | 0.85 | APLNR (0.56) | APLNRCYP2C19LMNAMTORGABRP | |
| SCHEMBL27900264 | 0.83 | APLNR (0.48) | APLNREPHX2GRM2GRM3GRM4 | |
| SCHEMBL8318891 | 0.81 | APLNR (0.65) | APLNRGRM2GRM3GRM4CYP1A2 | |
| SCHEMBL17212627 | 0.81 | APLNR (0.65) | APLNRGRM2GRM3GRM4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| EP-0472966-B1 | Esters and their use in perfumery | FIRMENICH & CIE (CH) | 1994-09-28 | — | — | EP | disclosed |
| US-5166412-A | ESTERS AND THEIR USE IN PERFUMERY | FIRMENICH S.A. (CH) | 1992-11-24 | — | — | US | disclosed |
| EP-0472966-A1 | Esters and their use in perfumery | FIRMENICH SA (CH) | 1992-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | APLNR 3457/4885EPHX2 768/4885GRM2 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.